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| Maya Rudolph | Dr. Vlam | |
| Natasha Lyonne | Nurse Tup | |
| Kieran Culkin | Dr. Plowp | |
| Keke Palmer | Dr. Klak | |
| Stephanie Hsu | Dr. Sleech | |
| Gary Anthony Williams | Flork 1 | |
| Lennon Parham | Flork 2 | |
| Andrew Dismukes | Matt | |
| Bowen Yang | Screechie 3 | |
| Sam Smith | Dr. Azel | |
| Phil LaMarr | ||
| Greta Lee | ||
| Abbi Jacobson | Dr. Zypha | |
| Kemah Bob | Ovu | |
| Tracee Ellis Ross | Mysoon | |
| Jay Ellis | Flim | |
| Cirocco Dunlap | ||
| Grey DeLisle | ||
| Macaulay Culkin | ||
| Rory Culkin | ||
| John Waters | ||
| Jessica Lowe | Luxex | |
| Christian Culkin | ||
| Shane Culkin |
| Director |
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| Producer |
Danielle Renfrew Behrens
Antonio Canobbio Cirocco Dunlap Robin Eisenberg Ben Kalina |
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| Writer | Cirocco Dunlap
Joanna Bradley Kirsten King Anne Lane |
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| Musician | Wendy & Lisa
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Sleech and Klak, two brilliant female alien doctors who specialize in rare sci-fi illnesses. |
| 2/23/2024 1. Sometimes Heads Break | |
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Sleech and Klak perform an enticing, dangerous, and super illegal surgery.
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| 2/23/2024 2. The Land of Sex and Death | |
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Sleech and Plowp wrangle an exploding patient. Outside the hospital, Klak deals with her mom, which is more stressful than an exploding patient.
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| 2/23/2024 3. Tomorrow's Death Is Yesterday's Problem | |
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Sleech and Klak treat a venture capitalist with an illicit time sickness and a great outfit.
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| 2/23/2024 4. The Curse of Orlosh | |
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A sexually transmitted infection spreads quickly through the very horny hospital.
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| 2/23/2024 5. Beef Sturgeon Sleech | |
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A surprising doctor is chosen as temporary chief surgeon. Klak develops a new crush, and Matt goes on a sexy hunt for alien limbs.
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| 2/23/2024 6. That's Science, Baby! | |
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Happy St. Cthonk's Day. (The St. stands for scientist). While Sleech and Matt unexpectedly spend the holiday together, Klak does something equally festive: an autopsy.
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| 2/23/2024 7. Just One More Adjustment | |
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The galaxy watches as Sleech tries to save Klak from herself. Unrelated, Matt and Plowp do a lot of crying.
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| 2/23/2024 8. Apocalypse Got You Down? | |
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Sleech and Klak try to save the world and end up in a surprisingly roomy digestive tract.
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